https://www.reforms-project.org.uk/published-study/ 2026-06-05T14:03:24+00:00 https://www.reforms-project.org.uk/published-study/efficacy-of-the-nccv-cocktail-1-vaccine-for-refractory-pediatric-solid-tumors-a-phase-i-clinical-trial/ 2026-06-05T14:02:21+00:00 https://www.reforms-project.org.uk/published-study/metronomic-chemotherapy-and-radiotherapy-as-salvage-treatment-in-refractory-or-relapsed-pediatric-solid-tumours/ 2026-06-05T14:02:21+00:00 https://www.reforms-project.org.uk/published-study/phase-ii-results-from-a-phase-i-ii-study-to-assess-the-safety-and-efficacy-of-weekly-nab-paclitaxel-in-paediatric-patients-with-recurrent-or-refractory-solid-tumours-a-collaboration-with-the-european/ 2026-06-05T14:02:21+00:00 https://www.reforms-project.org.uk/published-study/phase-i-trial-of-tirapazamine-and-cyclophosphamide-in-children-with-refractory-solid-tumors-a-pediatric-oncology-group-study/ 2026-06-05T14:02:21+00:00 https://www.reforms-project.org.uk/published-study/phase-1-trial-of-temsirolimus-in-combination-with-irinotecan-and-temozolomide-in-children-adolescents-and-young-adults-with-relapsed-or-refractory-solid-tumors-a-childrens-oncology-group-study/ 2026-06-05T14:02:21+00:00 https://www.reforms-project.org.uk/published-study/reduced-intensity-allogeneic-stem-cell-transplantation-in-children-and-young-adults-with-ultrahigh-risk-pediatric-sarcomas/ 2026-06-05T14:02:21+00:00 https://www.reforms-project.org.uk/published-study/a-phase-2-trial-of-trabectedin-in-children-with-recurrent-rhabdomyosarcoma-ewing-sarcoma-and-non-rhabdomyosarcoma-soft-tissue-sarcomas-a-report-from-the-childrens-oncology-group/ 2026-06-05T14:02:21+00:00 https://www.reforms-project.org.uk/published-study/a-phase-ii-trial-and-pharmacokinetic-study-of-oxaliplatin-in-children-with-refractory-solid-tumors-a-childrens-oncology-group-study/ 2026-06-05T14:02:21+00:00 https://www.reforms-project.org.uk/published-study/a-phase-i-study-of-perifosine-with-temsirolimus-for-recurrent-pediatric-solid-tumors/ 2026-06-05T14:02:21+00:00 https://www.reforms-project.org.uk/published-study/phase-ii-study-of-a-protracted-irinotecan-schedule-in-children-with-refractory-or-recurrent-soft-tissue-sarcoma/ 2026-06-05T14:02:21+00:00 https://www.reforms-project.org.uk/published-study/integrating-irinotecan-in-standard-chemotherapy-a-novel-dose-density-combination-for-high-risk-pediatric-sarcomas/ 2026-06-05T14:02:21+00:00 https://www.reforms-project.org.uk/published-study/a-phase-i-study-of-irinotecan-in-pediatric-patients-a-pediatric-oncology-group-study/ 2026-06-05T14:02:21+00:00 https://www.reforms-project.org.uk/published-study/the-amore-protocol-for-advanced-stage-and-recurrent-non-orbital-rhabdomyosarcoma-in-the-head-and-neck-region-of-children-a-radiation-oncology-view/ 2026-06-05T14:02:21+00:00 https://www.reforms-project.org.uk/published-study/a-phase-i-study-of-irinotecan-administered-on-a-weekly-schedule-in-pediatric-patients/ 2026-06-05T14:02:21+00:00 https://www.reforms-project.org.uk/published-study/phase-ii-trial-of-irinotecan-in-children-with-refractory-solid-tumors-a-childrens-oncology-group-study/ 2026-06-05T14:02:21+00:00 https://www.reforms-project.org.uk/published-study/phase-i-trial-of-seneca-valley-virus-ntx-010-in-children-with-relapsed-refractory-solid-tumors-a-report-of-the-childrens-oncology-group/ 2026-06-05T14:02:21+00:00 https://www.reforms-project.org.uk/published-study/vinorelbine-and-low-dose-cyclophosphamide-in-the-treatment-of-pediatric-sarcomas-pilot-study-for-the-upcoming-european-rhabdomyosarcoma-protocol/ 2026-06-05T14:02:21+00:00 https://www.reforms-project.org.uk/published-study/vinorelbine-in-previously-treated-advanced-childhood-sarcomas-evidence-of-activity-in-rhabdomyosarcoma/ 2026-06-05T14:02:21+00:00 https://www.reforms-project.org.uk/published-study/topotecan-carboplatin-regimen-for-refractory-recurrent-rhabdomyosarcoma-in-children-report-from-the-aieop-soft-tissue-sarcoma-committee/ 2026-06-05T14:02:21+00:00 https://www.reforms-project.org.uk/published-study/eve-cyclosporin-etoposide-vincristine-epirubicin-with-high-dose-cyclosporin-chemotherapy-selected-for-multidrug-resistance-modulation/ 2026-06-05T14:02:21+00:00 https://www.reforms-project.org.uk/published-study/nivolumab-in-children-and-young-adults-with-relapsed-or-refractory-solid-tumours-or-lymphoma-advl1412-a-multicentre-open-label-single-arm-phase-1-2-trial/ 2026-06-05T14:02:26+00:00 https://www.reforms-project.org.uk/published-study/bevacizumab-in-pediatric-patients-how-safe-is-it/ 2026-06-05T14:02:26+00:00 https://www.reforms-project.org.uk/published-study/temozolomide-in-resistant-or-relapsed-pediatric-solid-tumors/ 2026-06-05T14:02:26+00:00 https://www.reforms-project.org.uk/published-study/randomized-phase-ii-trial-of-vincristine-irinotecan-with-or-without-temozolomide-in-children-and-adults-with-relapsed-or-refractory-rhabdomyosarcoma-a-european-paediatric-soft-tissue-sarcoma-study-g/ 2026-06-05T14:02:26+00:00 https://www.reforms-project.org.uk/published-study/metro-smhop-01-metronomics-combination-with-cyclophosphamide-etoposide-and-valproic-acid-for-refractory-and-relapsing-pediatric-malignancies/ 2026-06-05T14:02:27+00:00 https://www.reforms-project.org.uk/published-study/phase-ii-prospective-open-label-study-of-everolimus-in-children-and-adolescents-with-recurrent-or-refractory-osteosarcoma-rhabdomyosarcoma-and-other-soft-tissue-sarcoma/ 2026-06-05T14:02:27+00:00 https://www.reforms-project.org.uk/published-study/phase-i-expansion-cohort-to-evaluate-the-combination-of-bevacizumab-sorafenib-and-low-dose-cyclophosphamide-in-children-and-young-adults-with-refractory-or-recurrent-solid-tumors/ 2026-06-05T14:02:27+00:00 https://www.reforms-project.org.uk/published-study/a-phase-i-trial-of-talazoparib-and-irinotecan-with-and-without-temozolomide-in-children-and-young-adults-with-recurrent-or-refractory-solid-malignancies/ 2026-06-05T14:02:27+00:00 https://www.reforms-project.org.uk/published-study/ceritinib-in-paediatric-patients-with-anaplastic-lymphoma-kinase-positive-malignancies-an-open-label-multicentre-phase-1-dose-escalation-and-dose-expansion-study/ 2026-06-05T14:02:27+00:00 https://www.reforms-project.org.uk/published-study/a-phase-i-study-of-cixutumumab-imc-a12-in-combination-with-temsirolimus-cci-779-in-children-with-recurrent-solid-tumors-a-childrens-oncology-group-phase-i-consortium-report/ 2026-06-05T14:02:27+00:00 https://www.reforms-project.org.uk/published-study/phase-i-study-of-depsipeptide-in-pediatric-patients-with-refractory-solid-tumors-a-childrens-oncology-group-report/ 2026-06-05T14:02:27+00:00 https://www.reforms-project.org.uk/published-study/pharmacokinetic-and-pharmacodynamic-study-of-tariquidar-xr9576-a-p-glycoprotein-inhibitor-in-combination-with-doxorubicin-vinorelbine-or-docetaxel-in-children-and-adolescents-with-refractory-sol/ 2026-06-05T14:02:27+00:00 https://www.reforms-project.org.uk/published-study/phase-1-study-of-dalotuzumab-monotherapy-and-ridaforolimus-dalotuzumab-combination-therapy-in-paediatric-patients-with-advanced-solid-tumours/ 2026-06-05T14:02:27+00:00 https://www.reforms-project.org.uk/published-study/cefixime-allows-greater-dose-escalation-of-oral-irinotecan-a-phase-i-study-in-pediatric-patients-with-refractory-solid-tumors/ 2026-06-05T14:02:28+00:00 https://www.reforms-project.org.uk/published-study/phase-i-ii-study-of-single-agent-lenvatinib-in-children-and-adolescents-with-refractory-or-relapsed-solid-malignancies-and-young-adults-with-osteosarcoma-itcc-050/ 2026-06-05T14:02:28+00:00 https://www.reforms-project.org.uk/published-study/advl1522-a-phase-2-study-of-lorvotuzumab-mertansine-imgn901-in-children-with-relapsed-or-refractory-wilms-tumor-rhabdomyosarcoma-neuroblastoma-pleuropulmonary-blastoma-malignant-peripheral-nerv/ 2026-06-05T14:02:28+00:00 https://www.reforms-project.org.uk/published-study/atezolizumab-for-children-and-young-adults-with-previously-treated-solid-tumours-non-hodgkin-lymphoma-and-hodgkin-lymphoma-imatrix-a-multicentre-phase-1-2-study/ 2026-06-05T14:02:28+00:00 https://www.reforms-project.org.uk/published-study/phase-ii-study-of-gemcitabine-combined-with-oxaliplatin-in-relapsed-or-refractory-paediatric-solid-malignancies-an-innovative-therapy-for-children-with-cancer-european-consortium-study/ 2026-06-05T14:02:28+00:00 https://www.reforms-project.org.uk/published-study/phase-i-study-of-weekly-oxaliplatin-in-relapsed-or-refractory-pediatric-solid-malignancies/ 2026-06-05T14:02:29+00:00 https://www.reforms-project.org.uk/published-study/pembrolizumab-in-paediatric-patients-with-advanced-melanoma-or-a-pd-l1-positive-advanced-relapsed-or-refractory-solid-tumour-or-lymphoma-keynote-051-interim-analysis-of-an-open-label-single-arm/ 2026-06-05T14:02:29+00:00 https://www.reforms-project.org.uk/published-study/phase-1-dose-escalation-and-pharmacokinetic-study-of-regorafenib-in-paediatric-patients-with-recurrent-or-refractory-solid-malignancies/ 2026-06-05T14:02:29+00:00 https://www.reforms-project.org.uk/published-study/phase-ii-trial-of-temsirolimus-in-children-with-high-grade-glioma-neuroblastoma-and-rhabdomyosarcoma/ 2026-06-05T14:02:29+00:00 https://www.reforms-project.org.uk/published-study/phase-i-study-of-decitabine-with-doxorubicin-and-cyclophosphamide-in-children-with-neuroblastoma-and-other-solid-tumors-a-childrens-oncology-group-study/ 2026-06-05T14:02:29+00:00 https://www.reforms-project.org.uk/published-study/phase-i-pharmacokinetic-and-pharmacodynamic-study-of-pazopanib-in-children-with-soft-tissue-sarcoma-and-other-refractory-solid-tumors-a-childrens-oncology-group-phase-i-consortium-report/ 2026-06-05T14:02:29+00:00 https://www.reforms-project.org.uk/published-study/topotecan-by-21-day-continuous-infusion-in-children-with-relapsed-or-refractory-solid-tumors-a-childrens-oncology-group-study/ 2026-06-05T14:02:29+00:00 https://www.reforms-project.org.uk/published-study/a-phase-1-pilot-study-of-radiofrequency-ablation-for-the-treatment-of-recurrent-pediatric-solid-tumors/ 2026-06-05T14:02:29+00:00 https://www.reforms-project.org.uk/published-study/immunotherapy-of-relapsed-and-refractory-solid-tumors-with-ex-vivo-expanded-multi-tumor-associated-antigen-specific-cytotoxic-t-lymphocytes-a-phase-i-study/ 2026-06-05T14:02:29+00:00 https://www.reforms-project.org.uk/published-study/lak-cell-therapy-and-whole-body-therapy-in-the-management-of-chemorefractory-tumors/ 2026-06-05T14:02:29+00:00 https://www.reforms-project.org.uk/published-study/phase-ii-trial-of-ixabepilone-administered-daily-for-five-days-in-children-and-young-adults-with-refractory-solid-tumors-a-report-from-the-childrens-oncology-group/ 2026-06-05T14:02:29+00:00 https://www.reforms-project.org.uk/published-study/pediatric-phase-i-and-pharmacokinetic-study-of-erlotinib-followed-by-the-combination-of-erlotinib-and-temozolomide-a-childrens-oncology-group-phase-i-consortium-study/ 2026-06-05T14:02:29+00:00 https://www.reforms-project.org.uk/published-study/treatment-outcome-following-transarterial-chemoembolization-in-advanced-bone-and-soft-tissue-sarcomas/ 2026-06-05T14:02:29+00:00 https://www.reforms-project.org.uk/published-study/phase-i-evaluation-of-oral-and-intravenous-vinorelbine-in-pediatric-cancer-patients-a-report-from-the-childrens-oncology-group/ 2026-06-05T14:02:29+00:00 https://www.reforms-project.org.uk/published-study/dose-finding-study-by-continuous-reassessment-method-crm-for-topotecan-tt-in-combination-with-ifosfamide-if-as-a-second-line-therapy-for-pediatric-solid-cancer-preliminary-report-of-phase-i-ii/ 2026-06-05T14:02:29+00:00 https://www.reforms-project.org.uk/published-study/oral-etoposide-for-recurrent-progressive-sarcomas-of-childhood/ 2026-06-05T14:02:30+00:00 https://www.reforms-project.org.uk/published-study/phase-i-study-of-oral-sonidegib-lde225-in-pediatric-brain-and-solid-tumors-and-a-phase-ii-study-in-children-and-adults-with-relapsed-medulloblastoma/ 2026-06-05T14:02:30+00:00 https://www.reforms-project.org.uk/published-study/a-feasibility-trial-of-antiangiogenic-metronomic-chemotherapy-in-pediatric-patients-with-recurrent-or-progressive-cancer/ 2026-06-05T14:02:30+00:00 https://www.reforms-project.org.uk/published-study/phase-2-trial-of-sorafenib-in-children-and-young-adults-with-refractory-solid-tumors-a-report-from-the-childrens-oncology-group/ 2026-06-05T14:02:30+00:00 https://www.reforms-project.org.uk/published-study/a-phase-i-trial-and-viral-clearance-study-of-reovirus-reolysin-in-children-with-relapsed-or-refractory-extra-cranial-solid-tumors-a-childrens-oncology-group-phase-i-consortium-report/ 2026-06-05T14:02:30+00:00 https://www.reforms-project.org.uk/published-study/a-phase-i-trial-combining-decitabine-dendritic-cell-vaccine-targeting-mage-a1-mage-a3-and-ny-eso-1-for-children-with-relapsed-or-therapy-refractory-neuroblastoma-and-sarcoma/ 2026-06-05T14:02:35+00:00 https://www.reforms-project.org.uk/published-study/phase-ii-evaluation-of-intravenous-vinorelbine-navelbine-in-recurrent-or-refractory-pediatric-malignancies-a-childrens-oncology-group-study/ 2026-06-05T14:02:35+00:00 https://www.reforms-project.org.uk/published-study/phase-i-clinical-trial-of-ifosfamide-oxaliplatin-and-etoposide-ioe-in-pediatric-patients-with-refractory-solid-tumors/ 2026-06-05T14:02:35+00:00 https://www.reforms-project.org.uk/published-study/phase-i-trial-of-rebeccamycin-analog-nsc655649-in-children-with-refractory-solid-tumors-a-pediatric-oncology-group-study/ 2026-06-05T14:02:35+00:00 https://www.reforms-project.org.uk/published-study/a-phase-ii-trial-of-rebeccamycin-analogue-nsc-655649-in-children-with-solid-tumors-a-childrens-oncology-group-study/ 2026-06-05T14:02:35+00:00 https://www.reforms-project.org.uk/published-study/phase-ii-study-of-temozolomide-and-topotecan-totem-in-children-with-relapsed-or-refractory-extracranial-and-central-nervous-system-tumors-including-medulloblastoma-with-post-hoc-bayesian-analysis-a/ 2026-06-05T14:02:35+00:00 https://www.reforms-project.org.uk/published-study/a-phase-ii-study-of-pazopanib-in-children-adolescents-and-young-adults-with-refractory-solid-tumors/ 2026-06-05T14:02:35+00:00 https://www.reforms-project.org.uk/published-study/efficacy-and-safety-of-the-vegfr2-inhibitor-apatinib-for-metastatic-soft-tissue-sarcoma-chinese-cohort-data-from-nct03121846/ 2026-06-05T14:02:35+00:00 https://www.reforms-project.org.uk/published-study/reduced-intensity-haploidentical-bone-marrow-transplantation-with-post-transplant-cyclophosphamide-for-solid-tumors-in-pediatric-and-young-adult-patients/ 2026-06-05T14:02:35+00:00 https://www.reforms-project.org.uk/published-study/outcome-of-pediatric-recurrent-and-refractory-malignant-solid-tumors-following-ifosfamide-carboplatin-etoposide-ice-a-phase-ii-study-in-a-pediatric-oncology-centre-in-brazil/ 2026-06-05T14:02:35+00:00 https://www.reforms-project.org.uk/published-study/registration-directed-phase-1-2-trial-of-irinotecan-for-pediatric-solid-tumors/ 2026-06-05T14:02:35+00:00 https://www.reforms-project.org.uk/published-study/dose-escalation-and-pharmacokinetics-of-pegylated-liposomal-doxorubicin-doxil-in-children-with-solid-tumors-a-pediatric-oncology-group-study/ 2026-06-05T14:02:35+00:00 https://www.reforms-project.org.uk/published-study/randomized-phase-ii-trial-of-bevacizumab-or-temsirolimus-in-combination-with-chemotherapy-for-first-relapse-rhabdomyosarcoma-a-report-from-the-childrens-oncology-group/ 2026-06-05T14:02:35+00:00 https://www.reforms-project.org.uk/published-study/randomized-phase-ii-window-trial-of-two-schedules-of-irinotecan-with-vincristine-in-patients-with-first-relapse-or-progression-of-rhabdomyosarcoma-a-report-from-the-childrens-oncology-group/ 2026-06-05T14:02:36+00:00 https://www.reforms-project.org.uk/published-study/a-phase-i-study-of-oxaliplatin-and-doxorubicin-in-pediatric-patients-with-relapsed-or-refractory-extracranial-non-hematopoietic-solid-tumors/ 2026-06-05T14:02:36+00:00 https://www.reforms-project.org.uk/published-study/phase-1-trial-of-olaratumab-monotherapy-and-in-combination-with-chemotherapy-in-pediatric-patients-with-relapsed-refractory-solid-and-central-nervous-system-tumors/ 2026-06-05T14:02:36+00:00 https://www.reforms-project.org.uk/published-study/risk-based-treatment-for-patients-with-first-relapse-or-progression-of-rhabdomyosarcoma-a-report-from-the-childrens-oncology-group/ 2026-06-05T14:02:38+00:00 https://www.reforms-project.org.uk/published-study/treatment-of-children-with-poor-risk-solid-tumors-by-further-escalation-of-the-vetopec-regimen-including-very-high-dose-cyclophosphamide-and-peripheral-stem-cell-support-an-australian-and-new-zealand/ 2026-06-05T14:02:39+00:00 https://www.reforms-project.org.uk/published-study/phase-1-study-of-oxaliplatin-and-irinotecan-in-pediatric-patients-with-refractory-solid-tumors-a-childrens-oncology-group-study/ 2026-06-05T14:02:39+00:00 https://www.reforms-project.org.uk/published-study/extended-phase-i-evaluation-of-vincristine-irinotecan-temozolomide-and-antibiotic-in-children-with-refractory-solid-tumors/ 2026-06-05T14:02:39+00:00 https://www.reforms-project.org.uk/published-study/efficacy-of-topotecan-plus-vincristine-and-doxorubicin-in-children-with-recurrent-refractory-rhabdomyosarcoma/ 2026-06-05T14:02:39+00:00 https://www.reforms-project.org.uk/published-study/prolonged-14-day-continuous-infusion-of-high-dose-ifosfamide-with-an-external-portable-pump-feasibility-and-efficacy-in-refractory-pediatric-sarcoma/ 2026-06-05T14:02:39+00:00 https://www.reforms-project.org.uk/published-study/phase-i-trial-and-pharmacokinetic-study-of-lexatumumab-in-pediatric-patients-with-solid-tumors/ 2026-06-05T14:02:39+00:00 https://www.reforms-project.org.uk/published-study/adjuvant-immunotherapy-to-improve-outcome-in-high-risk-pediatric-sarcomas/ 2026-06-05T14:02:39+00:00 https://www.reforms-project.org.uk/published-study/phase-i-clinical-trial-of-ipilimumab-in-pediatric-patients-with-advanced-solid-tumors/ 2026-06-05T14:02:39+00:00 https://www.reforms-project.org.uk/published-study/adoptive-cellular-immunotherapy-for-refractory-childhood-cancers-a-single-center-experience/ 2026-06-05T14:02:39+00:00 https://www.reforms-project.org.uk/published-study/phase-ii-study-of-vinorelbine-and-continuous-low-doses-cyclophosphamide-in-children-and-young-adults-with-a-relapsed-or-refractory-malignant-solid-tumour-good-tolerance-profile-and-efficacy-in-rhabdo/ 2026-06-05T14:02:39+00:00 https://www.reforms-project.org.uk/published-study/phase-i-results-of-a-phase-i-ii-study-of-weekly-nab-paclitaxel-in-paediatric-patients-with-recurrent-refractory-solid-tumours-a-collaboration-with-innovative-therapies-for-children-with-cancer/ 2026-06-05T14:02:39+00:00 https://www.reforms-project.org.uk/published-study/phase-i-study-of-vinblastine-and-sirolimus-in-pediatric-patients-with-recurrent-or-refractory-solid-tumors/ 2026-06-05T14:02:39+00:00 https://www.reforms-project.org.uk/published-study/a-phase-ii-study-of-alisertib-in-children-with-recurrent-refractory-solid-tumors-or-leukemia-childrens-oncology-group-phase-i-and-pilot-consortium-advl0921/ 2026-06-05T14:02:39+00:00 https://www.reforms-project.org.uk/published-study/phase-i-and-clinical-pharmacology-study-of-bevacizumab-sorafenib-and-low-dose-cyclophosphamide-in-children-and-young-adults-with-refractory-recurrent-solid-tumors/ 2026-06-05T14:02:39+00:00 https://www.reforms-project.org.uk/published-study/phase-1-trial-of-ontuxizumab-morab-004-in-children-with-relapsed-or-refractory-solid-tumors-a-report-from-the-childrens-oncology-group-phase-1-pilot-consortium-advl1213/ 2026-06-05T14:02:39+00:00 https://www.reforms-project.org.uk/published-study/natural-killer-cells-can-exert-a-graft-vs-tumor-effect-in-haploidentical-stem-cell-transplantation-for-pediatric-solid-tumors/ 2026-06-05T14:02:39+00:00 https://www.reforms-project.org.uk/published-study/randomized-phase-ii-study-of-carboplatin-and-irinotecan-or-irinotecan-in-1-21-year-old-patients-with-refractory-solid-tumors/ 2026-06-05T14:02:39+00:00 https://www.reforms-project.org.uk/published-study/metronomic-chemotherapy-vs-best-supportive-care-in-progressive-pediatric-solid-malignant-tumors-a-randomized-clinical-trial/ 2026-06-05T14:02:39+00:00 https://www.reforms-project.org.uk/published-study/allogeneic-stem-cell-transplantation-from-hla-identical-donor-in-high-risk-sarcoma/ 2026-06-05T14:02:50+00:00 https://www.reforms-project.org.uk/published-study/a-novel-trial-of-topotecan-ifosfamide-and-carboplatin-tic-in-children-with-recurrent-solid-tumors/ 2026-06-05T14:02:50+00:00 https://www.reforms-project.org.uk/published-study/pediatric-phase-i-trial-of-oral-sorafenib-and-topotecan-in-refractory-or-recurrent-pediatric-solid-malignancies/ 2026-06-05T14:02:50+00:00 https://www.reforms-project.org.uk/published-study/first-in-human-first-in-child-trial-of-autologous-mscs-carrying-the-oncolytic-virus-icovir-5-in-patients-with-advanced-tumors/ 2026-06-05T14:02:50+00:00 https://www.reforms-project.org.uk/published-study/phase-i-study-of-topotecan-in-combination-with-temozolomide-totem-in-relapsed-or-refractory-paediatric-solid-tumours/ 2026-06-05T14:02:50+00:00 https://www.reforms-project.org.uk/published-study/a-pilot-study-of-protracted-topotecan-dosing-using-a-pharmacokinetically-guided-dosing-approach-in-children-with-solid-tumors/ 2026-06-05T14:02:50+00:00 https://www.reforms-project.org.uk/published-study/feasibility-of-cancer-immunotherapy-with-wt1-peptide-vaccination-for-solid-and-hematological-malignancies-in-children/ 2026-06-05T14:02:50+00:00 https://www.reforms-project.org.uk/published-study/cyclophosphamide-plus-topotecan-in-children-with-recurrent-or-refractory-solid-tumors-a-pediatric-oncology-group-phase-ii-study/ 2026-06-05T14:02:50+00:00 https://www.reforms-project.org.uk/published-study/phase-1-2-trial-of-talazoparib-in-combination-with-temozolomide-in-children-and-adolescents-with-refractory-recurrent-solid-tumors-including-ewing-sarcoma-a-childrens-oncology-group-phase-1-consorti/ 2026-06-05T14:02:50+00:00 https://www.reforms-project.org.uk/published-study/irinotecan-for-children-with-relapsed-solid-tumors/ 2026-06-05T14:02:50+00:00 https://www.reforms-project.org.uk/published-study/high-dose-chemotherapy-with-autologous-hematopoietic-stem-cell-transplantation-in-the-treatment-of-high-risk-pediatric-rhabdomyosacroma-patients/ 2026-06-05T14:02:50+00:00 https://www.reforms-project.org.uk/published-study/successful-allogeneic-hematopoietic-cell-engraftment-after-a-minimal-conditioning-regimen-in-children-with-relapsed-or-refractory-solid-tumors/ 2026-06-05T14:02:50+00:00 https://www.reforms-project.org.uk/published-study/phase-i-clinical-and-pharmacologic-study-of-weekly-cisplatin-and-irinotecan-combined-with-amifostine-for-refractory-solid-tumors/ 2026-06-05T14:02:51+00:00 https://www.reforms-project.org.uk/published-study/a-pediatric-phase-i-trial-and-pharmacokinetic-study-of-ispinesib-a-childrens-oncology-group-phase-i-consortium-study/ 2026-06-05T14:02:51+00:00 https://www.reforms-project.org.uk/published-study/phase-i-clinical-trial-of-oxaliplatin-in-children-and-adolescents-with-refractory-solid-tumors/ 2026-06-05T14:02:51+00:00 https://www.reforms-project.org.uk/published-study/a-pilot-pharmacokinetic-and-antiangiogenic-biomarker-study-of-celecoxib-and-low-dose-metronomic-vinblastine-or-cyclophosphamide-in-pediatric-recurrent-solid-tumors/ 2026-06-05T14:02:51+00:00 https://www.reforms-project.org.uk/published-study/intratumoral-injection-of-hsv1716-an-oncolytic-herpes-virus-is-safe-and-shows-evidence-of-immune-response-and-viral-replication-in-young-cancer-patients/ 2026-06-05T14:02:51+00:00 https://www.reforms-project.org.uk/published-study/first-in-human-intravenous-seprehvir-in-young-cancer-patients-a-phase-1-clinical-trial/ 2026-06-05T14:02:51+00:00 https://www.reforms-project.org.uk/published-study/phase-i-study-of-glypican-3-derived-peptide-vaccine-therapy-for-patients-with-refractory-pediatric-solid-tumors/ 2026-06-05T14:02:58+00:00 https://www.reforms-project.org.uk/published-study/phase-ii-trial-of-irinotecan-in-children-with-relapsed-or-refractory-rhabdomyosarcoma-a-joint-study-of-the-french-society-of-pediatric-oncology-and-the-united-kingdom-childrens-cancer-study-group/ 2026-06-05T14:02:58+00:00 https://www.reforms-project.org.uk/published-study/phase-1-study-of-sirolimus-in-combination-with-oral-cyclophosphamide-and-topotecan-in-children-and-young-adults-with-relapsed-and-refractory-solid-tumors/ 2026-06-05T14:02:58+00:00 https://www.reforms-project.org.uk/published-study/phase-ii-study-of-gemcitabine-in-children-with-solid-tumors-of-mesenchymal-and-embryonic-origin/ 2026-06-05T14:02:58+00:00 https://www.reforms-project.org.uk/published-study/phase-i-trial-of-two-schedules-of-vincristine-oral-irinotecan-and-temozolomide-voit-for-children-with-relapsed-or-refractory-solid-tumors-a-childrens-oncology-group-phase-i-consortium-study/ 2026-06-05T14:02:58+00:00 https://www.reforms-project.org.uk/published-study/pilot-study-of-vincristine-oral-irinotecan-and-temozolomide-voit-regimen-combined-with-bevacizumab-in-pediatric-patients-with-recurrent-solid-tumors-or-brain-tumors/ 2026-06-05T14:02:58+00:00 https://www.reforms-project.org.uk/published-study/phase-ii-study-of-cixutumumab-in-combination-with-temsirolimus-in-pediatric-patients-and-young-adults-with-recurrent-or-refractory-sarcoma-a-report-from-the-childrens-oncology-group/ 2026-06-05T14:02:58+00:00 https://www.reforms-project.org.uk/published-study/phase-2-trial-of-pemetrexed-in-children-and-adolescents-with-refractory-solid-tumors-a-childrens-oncology-group-study/ 2026-06-05T14:02:58+00:00 https://www.reforms-project.org.uk/published-study/phase-2-trial-of-cixutumumab-in-children-adolescents-and-young-adults-with-refractory-solid-tumors-a-report-from-the-childrens-oncology-group/ 2026-06-05T14:02:58+00:00 https://www.reforms-project.org.uk/published-study/phase-i-trial-of-cisplatin-and-topotecan-in-children-with-recurrent-solid-tumors-childrens-cancer-group-study-0942/ 2026-06-05T14:02:58+00:00 https://www.reforms-project.org.uk/published-study/phase-i-trial-and-pharmacokinetic-study-of-ixabepilone-administered-daily-for-5-days-in-children-and-adolescents-with-refractory-solid-tumors/ 2026-06-05T14:02:58+00:00 https://www.reforms-project.org.uk/published-study/a-phase-i-trial-and-pharmacokinetic-study-of-sorafenib-in-children-with-refractory-solid-tumors-or-leukemias-a-childrens-oncology-group-phase-i-consortium-report/ 2026-06-05T14:02:58+00:00 https://www.reforms-project.org.uk/published-study/next-generation-personalised-medicine-for-high-risk-paediatric-cancer-patients-the-inform-pilot-study/ 2026-06-05T14:02:58+00:00 https://www.reforms-project.org.uk/published-study/high-dose-ifosfamide-with-hematopoietic-growth-factor-support-in-advanced-bone-and-soft-tissue-sarcomas/ 2026-06-05T14:02:58+00:00 https://www.reforms-project.org.uk/published-study/phase-ii-investigation-of-docetaxel-in-pediatric-patients-with-recurrent-solid-tumors-a-report-from-the-childrens-oncology-group/ 2026-06-05T14:02:58+00:00 https://www.reforms-project.org.uk/published-study/phase-i-or-ii-study-of-ribociclib-in-combination-with-topotecan-temozolomide-or-everolimus-in-children-with-advanced-malignancies-arms-a-and-b-of-the-acs-e-esmart-trial/ 2026-06-05T14:02:58+00:00 https://www.reforms-project.org.uk/published-study/phase-2-trial-of-cabozantinib-in-children-and-young-adults-with-refractory-sarcomas-wilms-tumor-and-rare-tumors-childrens-oncology-group-study-advl1622/ 2026-06-05T14:02:59+00:00 https://www.reforms-project.org.uk/published-study/a-phase-1-study-of-prexasertib-ly2606368-achk1-2-inhibitor-in-pediatric-patients-with-recurrent-or-refractory-solid-tumors-including-cns-tumors-a-report-from-the-childrens-oncology-grou/ 2026-06-05T14:02:59+00:00 https://www.reforms-project.org.uk/published-study/phase-1-2-study-of-elraglusib-9-ing-41-a-small-molecule-selective-glycogen-synthase-kinase-3-beta-gsk-3%ce%b2-inhibitor-alone-or-with-irinotecan-temozolomide-irinotecan-or-cyclophosphamide-topo/ 2026-06-05T14:02:59+00:00 https://www.reforms-project.org.uk/published-study/phase-ii-study-of-selumetinib-in-children-and-young-adults-with-tumors-harboring-activating-mitogen-activated-protein-kinase-pathway-genetic-alterations-arm-e-of-the-nci-cog-pediatric-match-trial/ 2026-06-05T14:03:06+00:00 https://www.reforms-project.org.uk/published-study/a-phase-i-study-of-the-cdk4-6-inhibitor-ribociclib-lee011-in-pediatric-patients-with-malignant-rhabdoid-tumors-neuroblastoma-and-other-solid-tumors/ 2026-06-05T14:03:06+00:00 https://www.reforms-project.org.uk/published-study/multicenter-feasibility-study-of-tumor-molecular-profiling-to-inform-therapeutic-decisions-in-advanced-pediatric-solid-tumors-the-individualized-cancer-therapy-icat-study/ 2026-06-05T14:03:06+00:00 https://www.reforms-project.org.uk/published-study/molecular-screening-for-cancer-treatment-optimization-moscato-01-in-pediatric-patients-a-single-institutional-prospective-molecular-stratification-trial/ 2026-06-05T14:03:06+00:00 https://www.reforms-project.org.uk/published-study/avelumab-in-paediatric-patients-with-refractory-or-relapsed-solid-tumours-dose-escalation-results-from-an-open-label-single-arm-phase-1-2-trial/ 2026-06-05T14:03:07+00:00 https://www.reforms-project.org.uk/published-study/low-dose-metronomic-topotecan-and-pazopanib-topaz-in-children-with-relapsed-or-refractory-solid-tumors-a-c17-canadian-phase-i-clinical-trial/ 2026-06-05T14:03:07+00:00 https://www.reforms-project.org.uk/published-study/a-phase-i-trial-of-metformin-in-combination-with-vincristine-irinotecan-and-temozolomide-in-children-with-relapsed-or-refractory-solid-and-central-nervous-system-tumors-a-report-from-the-national-p/ 2026-06-05T14:03:07+00:00 https://www.reforms-project.org.uk/published-study/first-in-child-phase-i-ii-study-of-the-dual-mtorc1-2-inhibitor-vistusertib-azd2014-as-monotherapy-and-in-combination-with-topotecan-temozolomide-in-childrenwith-advanced-malignancies-arms-e-and-f-o/ 2026-06-05T14:03:07+00:00 https://www.reforms-project.org.uk/published-study/phase-ii-and-biomarker-study-of-programmed-cell-death-protein-1-inhibitor-nivolumab-and-metronomic-cyclophosphamide-in-paediatric-relapsed-refractory-solid-tumours-arm-g-of-acse-esmart-a-tria/ 2026-06-05T14:03:07+00:00 https://www.reforms-project.org.uk/published-study/a-phase-i-ii-study-of-prexasertib-in-combination-with-irinotecan-in-patients-with-relapsed-refractory-desmoplastic-small-round-cell-tumor-and-rhabdomyosarcoma/ 2026-06-05T14:03:07+00:00 https://www.reforms-project.org.uk/published-study/first-phase-1-clinical-study-of-olaparib-in-pediatric-patients-with-refractory-solid-tumors/ 2026-06-05T14:03:07+00:00 https://www.reforms-project.org.uk/published-study/the-pediatric-precision-oncology-inform-registry-clinical-outcome-and-benefit-for-patients-with-very-high-evidence-targets/ 2026-06-05T14:03:07+00:00 https://www.reforms-project.org.uk/published-study/phase-i-trial-of-ganitumab-plus-dasatinib-to-cotarget-the-insulin-like-growth-factor-1-receptor-and-src-family-kinase-yes-in-rhabdomyosarcoma/ 2026-06-05T14:03:08+00:00 https://www.reforms-project.org.uk/published-study/molecular-profiling-identifies-targeted-therapy-opportunities-in-pediatric-solid-cancer/ 2026-06-05T14:03:08+00:00 https://www.reforms-project.org.uk/published-study/phase-i-clinical-trial-of-the-wee1-inhibitor-adavosertib-azd1775-with-irinotecan-in-children-with-relapsed-solid-tumors-a-cog-phase-i-consortium-report-advl1312/ 2026-06-05T14:03:11+00:00 https://www.reforms-project.org.uk/published-study/molecular-diagnostics-enables-detection-of-actionable-targets-the-pediatric-targeted-therapy-2-0-registry/ 2026-06-05T14:03:11+00:00 https://www.reforms-project.org.uk/published-study/toxicity-of-cytoreductive-surgery-and-hyperthermic-intraperitoneal-chemotherapy-hipec-in-pediatric-patients-with-rhabdomyosarcoma-early-phase-1-trial-experience-and-results/ 2026-06-05T14:03:11+00:00 https://www.reforms-project.org.uk/published-study/regorafenib-plus-vincristine-and-irinotecan-in-pediatric-patients-with-recurrent-refractory-solid-tumors-an-innovative-therapy-for-children-with-cancer-study/ 2026-06-05T14:03:11+00:00 https://www.reforms-project.org.uk/published-study/pediatric-phase-2-trial-of-a-wee1-inhibitor-adavosertib-azd1775-and-irinotecan-for-relapsed-neuroblastoma-medulloblastoma-and-rhabdomyosarcoma/ 2026-06-05T14:03:11+00:00 https://www.reforms-project.org.uk/published-study/phase-i-ii-study-of-the-parp-inhibitor-olaparib-in-combination-with-irinotecan-in-children-with-advanced-malignancies-arm-d-of-the-acse-esmart-trial/ 2026-06-05T14:03:11+00:00 https://www.reforms-project.org.uk/published-study/afatinib-in-paediatric-patients-with-recurrent-refractory-erbb-dysregulated-tumours-results-of-a-phase-i-expansion-trial/ 2026-06-05T14:03:11+00:00 https://www.reforms-project.org.uk/published-study/wt1-peptide-immunotherapy-for-cancer-in-children-and-young-adults/ 2026-06-05T14:03:11+00:00 https://www.reforms-project.org.uk/published-study/recommended-phase-2-dose-rp2d-for-abemaciclib-in-combination-with-irinotecan-irn-and-temozolomide-tmz-in-pediatric-patients-with-relapsed-refractory-solid-tumors-jpcs-part-a/ 2026-06-05T14:03:11+00:00 https://www.reforms-project.org.uk/published-study/erdafitinb-in-patients-with-fgfr-altered-tumors-results-from-the-nci-cog-pediatric-match-trial-arm-b-apec1621b/ 2026-06-05T14:03:11+00:00 https://www.reforms-project.org.uk/published-study/evaluation-of-the-immunological-response-of-childhood-cancer-patients-treated-with-a-personalized-peptide-vaccine-for-refractory-soft-tissue-tumor-a-four-case-series/ 2026-06-05T14:03:11+00:00 https://www.reforms-project.org.uk/published-study/pediatric-precision-medicine-at-the-national-cancer-center-japan-prospective-genomic-study-of-pediatric-patients-withcancer-as-part-of-the-top-gear-project/ 2026-06-05T14:03:11+00:00 https://www.reforms-project.org.uk/published-study/metro-pd1-phase-1-study-of-nivolumab-in-combination-with-metronomic-chemotherapy-in-children-and-adolescents-with-relapsing-refractory-solid-tumors/ 2026-06-05T14:03:11+00:00 https://www.reforms-project.org.uk/published-study/feasibility-of-functional-precision-medicine-for-guiding-treatment-of-relapsed-or-refractory-pediatric-cancers/ 2026-06-05T14:03:11+00:00 https://www.reforms-project.org.uk/published-study/phase-i-ii-study-of-the-wee1-inhibitor-adavosertib-azd1775-in-combination-with-carboplatin-in-children-with-advanced-malignancies-arm-c-of-the-acse-esmart-trial/ 2026-06-05T14:03:17+00:00 https://www.reforms-project.org.uk/published-study/molecular-guided-therapy-for-the-treatment-of-patients-with-relapsed-and-refractory-childhood-cancers-a-beat-childhood-cancer-research-consortium-trial/ 2026-06-05T14:03:17+00:00 https://www.reforms-project.org.uk/published-study/phase-i-trial-of-pazopanib-in-combination-with-irinotecan-and-temozolomide-pazit-for-children-and-young-adults-with-advanced-sarcoma/ 2026-06-05T14:03:19+00:00 https://www.reforms-project.org.uk/published-study/whole-genome-and-transcriptome-integrated-analyses-guide-clinical-care-of-pediatric-poor-prognosis-cancers/ 2026-06-05T14:03:19+00:00 https://www.reforms-project.org.uk/published-study/parc-a-phase-i-ii-study-evaluating-the-safety-and-activity-of-pegylated-recombinant-human-arginase-bct-100-in-relapsed-refractory-cancers-of-children-and-young-adults/ 2026-06-05T14:03:19+00:00 https://www.reforms-project.org.uk/published-study/a-phase-i-and-pharmacokinetic-study-of-plitidepsin-in-children-with-advanced-solid-tumours-an-innovative-therapies-for-children-with-cancer-itcc-study/ 2026-06-05T14:03:19+00:00 https://www.reforms-project.org.uk/published-study/autologous-her2-specific-car-t-cells-after-lymphodepletion-for-advanced-sarcoma-a-phase-1-trial/ 2026-06-05T14:03:19+00:00 https://www.reforms-project.org.uk/published-study/phase-ii-study-of-samotolisib-in-children-and-young-adults-with-tumors-harboring-phosphoinositide-3-kinase-mammalian-target-of-rapamycin-pathway-alterations-pediatric-match-apec1621d/ 2026-06-05T14:03:20+00:00 https://www.reforms-project.org.uk/published-study/precision-guided-treatment-in-high-risk-pediatric-cancers/ 2026-06-05T14:03:20+00:00 https://www.reforms-project.org.uk/published-study/pegylated-liposomal-doxorubicin-combined-with-cyclophosphamide-and-vincristine-in-pediatric-patients-with-relapsed-refractory-solid-tumor-a-single-arm-open-label-phase-i-study/ 2026-06-05T14:03:21+00:00 https://www.reforms-project.org.uk/published-study/palbociclib-in-solid-tumor-patients-with-genomic-alterations-in-the-cyclind-cdk4-6-ink4a-rb-pathway-results-from-national-cancer-institute-childrens-oncology-group-pediatric-molecular-analys/ 2026-06-05T14:03:22+00:00 https://www.reforms-project.org.uk/published-study/a-study-of-lenvatinib-mk-7902-in-pediatric-participants-with-relapsed-or-refractory-solid-malignancies-mk-7902-013-e7080-e7080-g000-231/ 2026-06-05T14:03:22+00:00 https://www.reforms-project.org.uk/published-study/comparative-analysis-of-rna-expression-in-a-single-institution-cohort-of-pediatric-cancer-patients-preprint/ 2026-06-05T14:03:22+00:00 https://www.reforms-project.org.uk/published-study/phase-ii-study-of-ulixertinib-in-children-and-young-adults-with-tumors-harboring-activating-mitogen-activated-protein-kinase-pathway-alterations-apec1621j-of-the-national-cancer-institute-children/ 2026-06-05T14:03:22+00:00 https://www.reforms-project.org.uk/published-study/a-phase-1-study-of-abi-009-nab-sirolimus-in-combination-with-temozolomide-and-irinotecan-in-pediatric-patients-with-recurrent-or-refractory-solid-tumors-including-cns-tumors-a-childrens-on/ 2026-06-05T14:03:23+00:00 https://www.reforms-project.org.uk/published-study/phase-1-study-of-nedd8-activating-enzyme-inhibitor-pevonedistat-in-combination-with-chemotherapy-in-pediatric-patients-with-recurrent-or-refractory-solid-tumors-advl1615/ 2026-06-05T14:03:23+00:00 https://www.reforms-project.org.uk/published-study/safety-and-feasibility-of-anlotinib-in-children-with-high-risk-recurrent-or-refractory-sarcomas-an-open-label-single-centre-single-arm-phase-ia-ib-trial/ 2026-06-05T14:03:23+00:00 https://www.reforms-project.org.uk/published-study/interleukin-15-armoured-gpc3-car-t-cells-for-patients-with-solid-cancers/ 2026-06-05T14:03:23+00:00 https://www.reforms-project.org.uk/published-study/efficacy-safety-and-pharmacokinetics-of-eribulin-as-monotherapy-or-in-combination-with-irinotecan-for-patients-with-pediatric-rhabdomyosarcoma-non-rhabdomyosarcoma-soft-tissue-sarcoma-or-ewing-sar/ 2026-06-05T14:03:24+00:00 https://www.reforms-project.org.uk/published-study/efficacy-safety-and-pharmacokinetics-of-eribulin-as-monotherapy-or-in-combination-with-irinotecan-for-patients-with-pediatric-rhabdomyosarcoma-non-rhabdomyosarcoma-soft-tissue-sarcoma-or-ewing-sar-2/ 2026-06-05T14:03:24+00:00 https://www.reforms-project.org.uk/published-study/a-phase-1-2-study-of-lenvatinib-in-combination-with-everolimus-in-recurrent-and-refractory-pediatric-and-young-adult-solid-tumors/ 2026-06-05T14:03:24+00:00